Woonghee Lee

Woonghee Lee

University of Colorado Denver

Assistant Professor

Department of Chemistry

  • #Artificial Intelligence / Machine Learning
  • #Automated NMR Analysis
  • #Big Data
  • #Biomolecular NMR
  • #Full Stack Development
  • #Infectious Disease
  • #Integrative Structural Biology
  • #Protein Allostery
  • #Protein Structure and Function
  • #Software Suite

Lab Overview

Prof. Lee’s group in the Department of Chemistry at the University of Colorado Denver is eager to contributing indispensable high-throughput tools for analyzing biochemical/biophysical data and making technological breakthroughs towards a better understanding of protein 3D structures in terms of their roles and behaviors in biological context. He is a developer of popular analytic software tools such as NMRFAM-SPARKY, I-PINE, PONDEROSA-C/S, PACSY, etc and majority of them are considered the `field standards.’ He is also an author of many Protein Data Bank (PDB) and Biological Magnetic Resonance Bank (BMRB) entries related to the common cold, Ebola, Wilson’s disease, protein folding mechanisms, etc. The group comprises a development team working on innovative methods and tools to understand the structures and functions of a biomolecule and a research team utilizing them to extract a scientific meaning at the molecular level. The PI always enjoys talking to self-motivated researchers.

Research Area

  • #Chemistry
  • #Cell biology
  • #Inorganic chemistry
  • #Software
  • #Biology
  • #Protein structure
  • #Nuclear magnetic resonance spectroscopy
  • #Computer science
  • #Software package
  • #Protein domain

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Related papers to
‘ Chemistry ‘ : 21

  • PONDEROSA-C/S: client–server based software package for automated protein 3D structure determination

    2014/09

    3.1 Impact Factor

    28 citations

    Woonghee Lee, Jaime L. Stark, John L. Markley

    DOI : 10.1007/S10858-014-9855-X

    • #Chemistry
    • #Database
    • #Software
    • #Visualization
    • #Critical assessment
    • #Electronic Supplementary Material
    • #Automation
    • #Download
    • #Client–server model
    • #Software package

All papers authored by
‘ Woonghee Lee ’ : 33

  • NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

    2015/04
    BIOINFORMATICS

    5.8 Impact Factor

    827 citations

    Woonghee Lee, Marco Tonelli, John L. Markley

    DOI : 10.1093/BIOINFORMATICS/BTU830

    • #Computer science
    • #World Wide Web
    • #Programming language
    • #Software
    • #Nuclear magnetic resonance spectroscopy
    • #Source code
    • #Interfacing
    • #Python (programming language)
    • #Automated data
    • #Web server
    • #Software package

Related papers to
‘ Chemistry ‘ : 21

  • PONDEROSA-C/S: client–server based software package for automated protein 3D structure determination

    2014/09
    JOURNAL OF BIOMOLECULAR NMR

    3.1 Impact Factor

    28 citations

    Woonghee Lee, Jaime L. Stark, John L. Markley

    DOI : 10.1007/S10858-014-9855-X

    • #Chemistry
    • #Database
    • #Software
    • #Visualization
    • #Critical assessment
    • #Electronic Supplementary Material
    • #Automation
    • #Download
    • #Client–server model
    • #Software package
  • Integrative NMR for biomolecular research

    2016/03
    JOURNAL OF BIOMOLECULAR NMR

    2.4 Impact Factor

    28 citations

    Woonghee Lee, Gabriel Cornilescu, Hesam Dashti, Hamid R. Eghbalnia, Marco Tonelli, William M. Westler, Samuel E. Butcher, Katherine A. Henzler-Wildman, John L. Markley

    DOI : 10.1007/S10858-016-0029-X

    • #Chemistry
    • #Human–computer interaction
    • #Bioinformatics
    • #Software
    • #Nuclear magnetic resonance spectroscopy
    • #Virtual machine
    • #Web service
    • #Functional features
    • #Laptop
    • #Software package
    • #Software download

Looking for

Graduate student

Postdoctoral Researcher

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Contact information

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All papers authored by
‘ Woonghee Lee ’ : 33

  • NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

    2015/04
    BIOINFORMATICS

    5.8 Impact Factor

    827 citations

    Woonghee Lee, Marco Tonelli, John L. Markley

    DOI : 10.1093/BIOINFORMATICS/BTU830

    • #Computer science
    • #World Wide Web
    • #Programming language
    • #Software
    • #Nuclear magnetic resonance spectroscopy
    • #Source code
    • #Interfacing
    • #Python (programming language)
    • #Automated data
    • #Web server
    • #Software package
  • Molecular insights into the recognition of N-terminal histone modifications by the BRPF1 bromodomain.

    2014/04
    JOURNAL OF MOLECULAR BIOLOGY

    4.3 Impact Factor

    67 citations

    Amanda Poplawski, Kaifeng Hu, Woonghee Lee, Senthil Natesan, Danni Peng, Samuel Carlson, Xiaobing Shi, Stefan Balaz, John L. Markley, Karen C. Glass

    DOI : 10.1016/J.JMB.2013.12.007

    • #Biology
    • #Molecular biology
    • #Cell biology
    • #Chromatin
    • #Histone
    • #Binding selectivity
    • #Zinc finger
    • #Histone acetyltransferase
    • #Bromodomain
    • #Chromatin binding
    • #Acetyllysine

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