Doeke Romke Hekstra

Doeke Romke Hekstra

Harvard University

Assistant Professor

Applied Physics

Research Area

  • #Electric field
  • #Protein structure
  • #Cefotaxime
  • #Allosteric regulation
  • #Protein crystallization
  • #Biology
  • #Genetics
  • #Enzyme
  • #Evolvability
  • #Mutation

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Related papers to
‘ Electric field ‘ : 2

  • Electric-field-stimulated protein mechanics

    2016/12

    40.1 Impact Factor

    93 citations

    Doeke R. Hekstra, K. Ian White, Michael A. Socolich, Robert Henning, Vukica Šrajer, Rama Ranganathan

    DOI : 10.1038/NATURE20571

    • #Physics
    • #Mechanics
    • #Atom
    • #Electric field
    • #Protein structure
    • #PDZ domain
    • #Ligand (biochemistry)
    • #Drug discovery
    • #Allosteric regulation
    • #Protein crystallization

All papers authored by
‘ Doeke Romke Hekstra ’ : 4

  • Evolvability as a function of purifying selection in TEM-1 β-lactamase.

    2015/02
    CELL

    29.3 Impact Factor

    184 citations

    Michael A. Stiffler, Doeke R. Hekstra, Rama Ranganathan

    DOI : 10.1016/J.CELL.2015.01.035

    • #Biology
    • #Genetics
    • #Enzyme
    • #Evolvability
    • #Mutation
    • #Cefotaxime
    • #Negative selection
    • #Biochemical Activity
    • #Amp resistance
    • #Fitness effects

Related papers to
‘ Electric field ‘ : 2

  • Electric-field-stimulated protein mechanics

    2016/12
    NATURE

    40.1 Impact Factor

    93 citations

    Doeke R. Hekstra, K. Ian White, Michael A. Socolich, Robert Henning, Vukica Šrajer, Rama Ranganathan

    DOI : 10.1038/NATURE20571

    • #Physics
    • #Mechanics
    • #Atom
    • #Electric field
    • #Protein structure
    • #PDZ domain
    • #Ligand (biochemistry)
    • #Drug discovery
    • #Allosteric regulation
    • #Protein crystallization
  • Analysis of electric-field stimulated time-resolved X-ray crystallography data

    2019/07
    ACTA CRYSTALLOGRAPHICA SECTION A

    2.1 Impact Factor

    0 citations

    Doeke R. Hekstra, B.R. Lee, K.M. Dalton, Rama Ranganathan

    DOI : 10.1107/S0108767319096077

    • #Materials science
    • #Crystallography
    • #Electric field
    • #X-ray crystallography

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Contact information

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All papers authored by
‘ Doeke Romke Hekstra ’ : 4

  • Evolvability as a function of purifying selection in TEM-1 β-lactamase.

    2015/02
    CELL

    29.3 Impact Factor

    184 citations

    Michael A. Stiffler, Doeke R. Hekstra, Rama Ranganathan

    DOI : 10.1016/J.CELL.2015.01.035

    • #Biology
    • #Genetics
    • #Enzyme
    • #Evolvability
    • #Mutation
    • #Cefotaxime
    • #Negative selection
    • #Biochemical Activity
    • #Amp resistance
    • #Fitness effects
  • Polymeric peptide pigments with sequence-encoded properties

    2017/06
    SCIENCE

    41.1 Impact Factor

    127 citations

    Ayala Lampel, Scott A. McPhee, Hang-Ah Park, Gary G. Scott, Sunita Humagain, Doeke R. Hekstra, Barney Yoo, Pim W. J. M. Frederix, Tai-De Li, Rinat R. Abzalimov, Steven G. Greenbaum, Tell Tuttle, Chunhua Hu, Christopher J. Bettinger, Rein V. Ulijn

    DOI : 10.1126/SCIENCE.AAL5005

    • #Chemistry
    • #Polymer chemistry
    • #Combinatorial chemistry
    • #Amino acid
    • #Peptide
    • #Protein structure
    • #Covalent bond
    • #Small molecule
    • #Polymerization
    • #Peptide sequence
    • #Tripeptide

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