Leona D. Samson

Leona D. Samson

Massachusetts Institute of Technology

Professor

Department of Biological Engineering

Research Area

  • #Biology
  • #DNA repair
  • #DNA damage
  • #Base excision repair
  • #Cancer research
  • #Cell biology
  • #Chemistry
  • #DNA
  • #Molecular biology
  • #Nucleotide excision repair

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Related papers to
‘ Biology ‘ : 17

  • ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

    2018/05

    30.6 Impact Factor

    174 citations

    Jianfeng Shen, Zhenlin Ju, Wei Zhao, Lulu Wang, Yang Peng, Zhongqi Ge, Zachary D. Nagel, Jun Zou, Chen Wang, Prabodh Kapoor, Xiangyi Ma, Ding Ma, Jiyong Liang, Shumei Song, Jinsong Liu, Leona D. Samson, Jaffer A. Ajani, Guo Min Li, H. Liang, Xuetong Shen, Gordon B. Mills, Guang Peng

    DOI : 10.1038/S41591-018-0012-Z

    • #Biology
    • #Cancer research
    • #Cancer
    • #Mutation
    • #Immunotherapy
    • #Mutagenesis
    • #DNA mismatch repair
    • #Immune checkpoint
    • #MSH2
    • #Microsatellite instability

All papers authored by
‘ Leona D. Samson ’ : 32

  • ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

    2018/05
    NATURE MEDICINE

    30.6 Impact Factor

    174 citations

    Jianfeng Shen, Zhenlin Ju, Wei Zhao, Lulu Wang, Yang Peng, Zhongqi Ge, Zachary D. Nagel, Jun Zou, Chen Wang, Prabodh Kapoor, Xiangyi Ma, Ding Ma, Jiyong Liang, Shumei Song, Jinsong Liu, Leona D. Samson, Jaffer A. Ajani, Guo Min Li, H. Liang, Xuetong Shen, Gordon B. Mills, Guang Peng

    DOI : 10.1038/S41591-018-0012-Z

    • #Biology
    • #Cancer research
    • #Cancer
    • #Mutation
    • #Immunotherapy
    • #Mutagenesis
    • #DNA mismatch repair
    • #Immune checkpoint
    • #MSH2
    • #Microsatellite instability

Related papers to
‘ Biology ‘ : 17

  • ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

    2018/05
    NATURE MEDICINE

    30.6 Impact Factor

    174 citations

    Jianfeng Shen, Zhenlin Ju, Wei Zhao, Lulu Wang, Yang Peng, Zhongqi Ge, Zachary D. Nagel, Jun Zou, Chen Wang, Prabodh Kapoor, Xiangyi Ma, Ding Ma, Jiyong Liang, Shumei Song, Jinsong Liu, Leona D. Samson, Jaffer A. Ajani, Guo Min Li, H. Liang, Xuetong Shen, Gordon B. Mills, Guang Peng

    DOI : 10.1038/S41591-018-0012-Z

    • #Biology
    • #Cancer research
    • #Cancer
    • #Mutation
    • #Immunotherapy
    • #Mutagenesis
    • #DNA mismatch repair
    • #Immune checkpoint
    • #MSH2
    • #Microsatellite instability
  • Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis

    2014/05
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

    9.7 Impact Factor

    96 citations

    Zachary D. Nagel, Carrie Marie Margulies, Isaac A. Chaim, Siobhan K. McRee, Patrizia Mazzucato, Anwaar Ahmad, Ryan Abo, Vincent L. Butty, Anthony L. Forget, Leona D. Samson

    DOI : 10.1073/PNAS.1401182111

    • #Biology
    • #Genetics
    • #DNA damage
    • #DNA repair
    • #Mutagenesis
    • #Nucleotide excision repair
    • #DNA mismatch repair
    • #Base excision repair
    • #Non-homologous end joining
    • #Host-Cell Reactivation

Get access to
Contact information

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All papers authored by
‘ Leona D. Samson ’ : 32

  • ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

    2018/05
    NATURE MEDICINE

    30.6 Impact Factor

    174 citations

    Jianfeng Shen, Zhenlin Ju, Wei Zhao, Lulu Wang, Yang Peng, Zhongqi Ge, Zachary D. Nagel, Jun Zou, Chen Wang, Prabodh Kapoor, Xiangyi Ma, Ding Ma, Jiyong Liang, Shumei Song, Jinsong Liu, Leona D. Samson, Jaffer A. Ajani, Guo Min Li, H. Liang, Xuetong Shen, Gordon B. Mills, Guang Peng

    DOI : 10.1038/S41591-018-0012-Z

    • #Biology
    • #Cancer research
    • #Cancer
    • #Mutation
    • #Immunotherapy
    • #Mutagenesis
    • #DNA mismatch repair
    • #Immune checkpoint
    • #MSH2
    • #Microsatellite instability
  • The human gut bacterial genotoxin colibactin alkylates DNA

    2019/02
    SCIENCE

    41.8 Impact Factor

    150 citations

    Matthew R. Wilson, Yindi Jiang, Peter W. Villalta, Alessia Stornetta, Paul D. Boudreau, Andrea Carrá, Caitlin A. Brennan, Eunyoung Chun, Lizzie Ngo, Leona D. Samson, Bevin P. Engelward, Wendy S. Garrett, Silvia Balbo, Emily P. Balskus

    DOI : 10.1126/SCIENCE.AAR7785

    • #Chemistry
    • #Biochemistry
    • #DNA
    • #Metabolite
    • #Escherichia coli
    • #Pathogenesis
    • #Human gut
    • #Colorectal carcinogenesis
    • #Colibactin
    • #Adductomics

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