Bruce Tidor

Bruce Tidor

Massachusetts Institute of Technology

Professor

Department of Biological Engineering

Department of Electrical Engineering and Computer Science

Research Area

  • #Chemistry
  • #Biology
  • #Drug resistance
  • #Molecular dynamics
  • #Biochemistry
  • #Bayesian probability
  • #Catalysis
  • #Combinatorial chemistry
  • #Importance sampling
  • #Linearization

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Related papers to
‘ Chemistry ‘ : 3

  • Intramolecular Hydrogen Bonding Restricts Gd–Aqua‐Ligand Dynamics

    2017/05

    12.1 Impact Factor

    11 citations

    Eszter Boros, Raja Srinivas, Hee‐Kyung Kim, Arnold M. Raitsimring, Andrei V. Astashkin, Oleg G. Poluektov, Jens Niklas, Andrew D. Horning, Bruce Tidor, Peter Caravan

    DOI : 10.1002/ANIE.201702274

    • #Chemistry
    • #Crystallography
    • #Ligand
    • #Molecular dynamics
    • #Intramolecular force
    • #Acceptor
    • #Rotation around a fixed axis
    • #Hydrogen bond
    • #Molecular model
    • #Gadolinium

All papers authored by
‘ Bruce Tidor ’ : 8

  • Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution

    2016/03
    CELL

    30.4 Impact Factor

    98 citations

    Boyang Zhao, Joseph C. Sedlak, Raja Srinivas, Pau Creixell, Justin R. Pritchard, Bruce Tidor, Douglas A. Lauffenburger, Michael Hemann

    DOI : 10.1016/J.CELL.2016.01.045

    • #Biology
    • #Genetics
    • #Computational biology
    • #Drug resistance
    • #Computational model
    • #Collateral
    • #Initial treatment
    • #Phenotype
    • #Lymphoblastic Leukemia
    • #Philadelphia chromosome
    • #Somatic evolution in cancer

Related papers to
‘ Chemistry ‘ : 3

  • Intramolecular Hydrogen Bonding Restricts Gd–Aqua‐Ligand Dynamics

    2017/05
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

    12.1 Impact Factor

    11 citations

    Eszter Boros, Raja Srinivas, Hee‐Kyung Kim, Arnold M. Raitsimring, Andrei V. Astashkin, Oleg G. Poluektov, Jens Niklas, Andrew D. Horning, Bruce Tidor, Peter Caravan

    DOI : 10.1002/ANIE.201702274

    • #Chemistry
    • #Crystallography
    • #Ligand
    • #Molecular dynamics
    • #Intramolecular force
    • #Acceptor
    • #Rotation around a fixed axis
    • #Hydrogen bond
    • #Molecular model
    • #Gadolinium
  • Machine Learning Identifies Chemical Characteristics That Promote Enzyme Catalysis

    2019/02
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

    14.6 Impact Factor

    7 citations

    Brian M Bonk, James W Weis, Bruce Tidor

    DOI : 10.1021/JACS.8B13879

    • #Chemistry
    • #Artificial intelligence
    • #Machine learning
    • #Molecular dynamics
    • #Extramural
    • #Enzyme catalysis
    • #Substrate specificity

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Contact information

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All papers authored by
‘ Bruce Tidor ’ : 8

  • Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution

    2016/03
    CELL

    30.4 Impact Factor

    98 citations

    Boyang Zhao, Joseph C. Sedlak, Raja Srinivas, Pau Creixell, Justin R. Pritchard, Bruce Tidor, Douglas A. Lauffenburger, Michael Hemann

    DOI : 10.1016/J.CELL.2016.01.045

    • #Biology
    • #Genetics
    • #Computational biology
    • #Drug resistance
    • #Computational model
    • #Collateral
    • #Initial treatment
    • #Phenotype
    • #Lymphoblastic Leukemia
    • #Philadelphia chromosome
    • #Somatic evolution in cancer
  • Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library.

    2016/10
    JOURNAL OF BIOLOGICAL CHEMISTRY

    4.1 Impact Factor

    26 citations

    Michael W. Traxlmayr, Jonathan D. Kiefer, Raja Srinivas, Elisabeth Lobner, Alison W. Tisdale, Naveen K Mehta, Nicole J. Yang, Bruce Tidor, K. Dane Wittrup

    DOI : 10.1074/JBC.M116.741314

    • #Biology
    • #Biochemistry
    • #Amino acid
    • #Binding site
    • #Glycosylation
    • #Scaffold protein
    • #Epitope
    • #Aromatic amino acids
    • #Directed evolution
    • #Sulfolobus solfataricus

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